Figures

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Weekly admissions, available outcome data, organ support

Age and sex distribution (for period 2020-07-06 to 2020-08-02)

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Organ support required (at admission)

Organ support duration (for those patients that received organ support)

Tables - Patient Characteristics

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Patient characteristics: demographics (period 2020-07-06 to 2020-08-02; total admissions n=22)
Age at admission in years [n=22 (100.0%)]
Mean (SD) 47.59 (20.55)
Median (IQR) 47.25 (37.80,62.10)
Sex, n (%) [n=22 (100.0%)]
Female 3 (13.6%)
Male 19 (86.4%)
Pregnancy status, n (% of females) [n=2 (66.7%)]
Not known to be pregnant 2 (100.0%)
Recently pregnant 0 ( 0.0%)
Currently pregnant 0 ( 0.0%)
Body mass index categories, n (%) [n=22 (100.0%)]
<18.5 10 (45.5%)
18.5-<25 8 (36.4%)
25-<30 3 (13.6%)
30-<40 1 ( 4.5%)
40+ 0 ( 0.0%)
Patient characteristics: medical history (period 2020-07-06 to 2020-08-02; total admissions n=22)
Dependency prior to admission, n (%) [n=22 (100.0%)]
Able to live without assistance in daily activities 9 (40.9%)
Minor assistance with some daily activities 13 (59.1%)
Major assistance with majority of or all daily activities 0 ( 0.0%)
Total assistance with all daily activities 0 ( 0.0%)
HIV, n (%) [n=16 (72.7%)]
No HIV 10 (62.5%)
ART compliant 5 (31.2%)
ART non-compliant 0 ( 0.0%)
Not on ART 1 ( 6.2%)
TB, n (%) [n=22 (100.0%)]
No TB 21 (95.5%)
TB 1 ( 4.5%)
Hyptertension, n (%) [n=20 (90.9%)]
No severe hypertension 20 (100.0%)
Hypertension 0 ( 0.0%)
Congestive cardiac failure, n (%) [n=22 (100.0%)]
No congestive cardiac failure 22 (100.0%)
Congestive cardiac failure 0 ( 0.0%)
Stroke, n (%) [n=22 (100.0%)]
No stroke 22 (100.0%)
Stroke 0 ( 0.0%)
Diabetes, n (%) [n=22 (100.0%)]
No diabetes 22 (100.0%)
On insulin 0 ( 0.0%)
On tablets 0 ( 0.0%)
Not on treatment 0 ( 0.0%)
Patient characteristics: acute severity (period 2020-07-06 to 2020-08-02; total admissions n=22)
NEWS2 score [n=22 (100.0%)]
Median (IQR) 6.5 (5.25,9.75) (5.25,9.75)
UVA score [n=16 (72.7%)]
Median (IQR) 2.5 (1,5) (1,5)
PF ratio [n=22 (100.0%)]
Mean (SD) 31.03 (13.23) (13.23)
Median (IQR) 23.39 (20.62,44.41) (20.62,44.41)
[0,13.3) 0 ( 0.0%) (0.0%)
[13.3,26.7) 12 (54.5%) (54.5%)
[26.7,Inf) 10 (45.5%) (45.5%)

Tables - Outcomes

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Patient outcomes (period 2020-07-06 to 2020-08-02; total admissions n=22)
Outcome at the end of critical care, n (%) [n=22 (100.0%)]
Discharged 13 (59.1%)
Died 6 (27.3%)
Absconded 0 ( 0.0%)
Unknown 3 (13.6%)
Length of stay [n=20 (90.9%)]
Mean (SD) 4.05 (2.61)
Median (IQR) 3.50 (2.00,6.00)
Length of stay (critical care survivors; N=13) [n=13 (100.0%)]
Mean (SD) 3.46 (2.67)
Median (IQR) 3.00 (2.00,4.00)
Length of stay (critical care non survivors; N=6) [n=6 (100.0%)]
Mean (SD) 5.17 (2.48)
Median (IQR) 5.50 (3.50,6.00)
Organ support (at any time during critical care stay), n (%) [n=22 (100.0%)]
Oxygen 20 (90.9%)
Fluid balance 10 (45.5%)
Neurological observation 5 (22.7%)
Intravenous drug (not vasoactive) 2 ( 9.1%)
Intravenous drug (vasoactive) 0 ( 0.0%)
Continuous monitoring 20 (90.9%)
Intubation & ventilation 2 ( 9.1%)
Other 9 (40.9%)
Duration of oxygen support (days) [n=20 (100.0%)]
Mean (SD) 2.85 (2.11)
Median (IQR) 2.00 (1.00,3.25)
Duration of fluid balance (days) [n=10 (100.0%)]
Mean (SD) 3.10 (2.38)
Median (IQR) 2.00 (1.00,5.75)
Duration of neurological observation (days) [n=5 (100.0%)]
Mean (SD) 1.40 (0.55)
Median (IQR) 1.00 (1.00,2.00)
Duration of intravenous drug administration (not vasoactive) (days) [n=2 (100.0%)]
Mean (SD) 1.00 (0.00)
Median (IQR) 1.00 (1.00,1.00)
Duration of intravenous drug administration (vasoactive) (days) [n=0 (NaN%)]
Mean (SD) NaN (-)
Median (IQR) (-,-)
Duration of continuous monitoring (days) [n=20 (100.0%)]
Mean (SD) 2.70 (2.30)
Median (IQR) 1.50 (1.00,3.25)
Duration of intubation & ventilation (days) [n=2 (100.0%)]
Mean (SD) 1.00 (0.00)
Median (IQR) 1.00 (1.00,1.00)
Duration of other organ support (days) [n=9 (100.0%)]
Mean (SD) 2.11 (1.05)
Median (IQR) 2.00 (1.00,3.00)
Patient characteristics by outcome (period 2020-07-06 to 2020-08-02; total admissions n=22)
Discharged (hospital)
Discharged (critical care), died in hospital
Died in critical care
Discharged (critical care), outcome unknown
Outcome unknown
Age [n=22 (100.0%)]
0-29 0 (0.0%) 0 (0.0%) 1 (50.0%) 0 (0.0%) 0 (0.0%)
30-39 0 (0.0%) 0 (0.0%) 1 (16.7%) 0 (0.0%) 0 (0.0%)
40-49 0 (0.0%) 0 (0.0%) 0 ( 0.0%) 0 (0.0%) 0 (0.0%)
50-59 0 (0.0%) 0 (0.0%) 2 (66.7%) 0 (0.0%) 0 (0.0%)
60+ 0 (0.0%) 0 (0.0%) 2 (28.6%) 0 (0.0%) 0 (0.0%)
Sex [n=22 (100.0%)]
Female 0 (0.0%) 0 (0.0%) 0 ( 0.0%) 0 (0.0%) 0 (0.0%)
Male 0 (0.0%) 0 (0.0%) 6 (31.6%) 0 (0.0%) 0 (0.0%)
BMI [n=22 (100.0%)]
<18.5 0 (0.0%) 0 (0.0%) 2 (20.0%) 0 (0.0%) 0 (0.0%)
18.5-<25 0 (0.0%) 0 (0.0%) 2 (25.0%) 0 (0.0%) 0 (0.0%)
25-<30 0 (0.0%) 0 (0.0%) 2 (66.7%) 0 (0.0%) 0 (0.0%)
30-<40 0 (0.0%) 0 (0.0%) 0 ( 0.0%) 0 (0.0%) 0 (0.0%)
40+ 0 (NaN%) 0 (NaN%) 0 ( NaN%) 0 (NaN%) 0 (NaN%)
HIV status [n=16 (72.7%)]
No HIV 0 (0.0%) 0 (0.0%) 2 ( 20.0%) 0 (0.0%) 0 (0.0%)
ART compliant 0 (0.0%) 0 (0.0%) 1 ( 20.0%) 0 (0.0%) 0 (0.0%)
ART non-compliant 0 (NaN%) 0 (NaN%) 0 ( NaN%) 0 (NaN%) 0 (NaN%)
Not on ART 0 (0.0%) 0 (0.0%) 1 (100.0%) 0 (0.0%) 0 (0.0%)
TB status [n=22 (100.0%)]
No TB 0 (0.0%) 0 (0.0%) 5 ( 23.8%) 0 (0.0%) 0 (0.0%)
TB 0 (0.0%) 0 (0.0%) 1 (100.0%) 0 (0.0%) 0 (0.0%)
NEWS2 score [n=22 (100.0%)]
Mean (SD) (-) (-) 9.83 (2.14) (-) (-)
Median (IQR) (-,-) (-,-) 10.50 ( 9.25,11.00) (-,-) (-,-)
UVA score [n=16 (72.7%)]
Mean (SD) (-) (-) 3.50 (1.91) (-) (-)
Median (IQR) (-,-) (-,-) 4.00 (2.50,5.00) (-,-) (-,-)
Length of stay (days) [n=20 (90.9%)]
Mean (SD) (-) (-) 5.17 (2.48) (-) (-)
Median (IQR) (-,-) (-,-) 5.50 (3.50,6.00) (-,-) (-,-)
Organ support (at any time during critical care) [n=22 (100.0%)]
Oxygen 0 (0.0%) 0 (0.0%) 6 (30.0%) 0 (0.0%) 0 (0.0%)
Fluid balance 0 (0.0%) 0 (0.0%) 4 (40.0%) 0 (0.0%) 0 (0.0%)
Neurological observation 0 (0.0%) 0 (0.0%) 3 (60.0%) 0 (0.0%) 0 (0.0%)
Intravenous drug (not vasoactive) 0 (0.0%) 0 (0.0%) 1 (50.0%) 0 (0.0%) 0 (0.0%)
Intravenous drug (vasoactive) 0 (NaN%) 0 (NaN%) 0 ( NaN%) 0 (NaN%) 0 (NaN%)
Continuous monitoring 0 (0.0%) 0 (0.0%) 6 (30.0%) 0 (0.0%) 0 (0.0%)
Intubation & ventilation 0 (0.0%) 0 (0.0%) 1 (50.0%) 0 (0.0%) 0 (0.0%)
Other 0 (0.0%) 0 (0.0%) 2 (22.2%) 0 (0.0%) 0 (0.0%)
Duration of oxygen support (days) [n=20 (100.0%)]
Mean (SD) (-) (-) 4.00 (2.45) (-) (-)
Median (IQR) (-,-) (-,-) 3.00 (2.25,5.25) (-,-) (-,-)
Duration of fluid balance (days) [n=10 (100.0%)]
Mean (SD) (-) (-) 4.00 (2.45) (-) (-)
Median (IQR) (-,-) (-,-) 4.50 (2.50,6.00) (-,-) (-,-)
Duration of neurological observation (days) [n=5 (100.0%)]
Mean (SD) (-) (-) 1.67 (0.58) (-) (-)
Median (IQR) (-,-) (-,-) 2.00 (1.50,2.00) (-,-) (-,-)
Duration of intravenous drug administration (not vasoactive) (days) [n=2 (100.0%)]
Mean (SD) (-) (-) 1.00 (-) (-) (-)
Median (IQR) (-,-) (-,-) 1.00 (1.00,1.00) (-,-) (-,-)
Duration of intravenous drug administration (vasoactive) (days) [n=0 (NaN%)]
Mean (SD) (-) (-) (-) (-) (-)
Median (IQR) (-,-) (-,-) (-,-) (-,-) (-,-)
Duration of continuous monitoring (days) [n=20 (100.0%)]
Mean (SD) (-) (-) 4.00 (2.45) (-) (-)
Median (IQR) (-,-) (-,-) 3.00 (2.25,5.25) (-,-) (-,-)
Duration of intubation & ventilation (days) [n=2 (100.0%)]
Mean (SD) (-) (-) 1.00 (-) (-) (-)
Median (IQR) (-,-) (-,-) 1.00 (1.00,1.00) (-,-) (-,-)
Duration of other organ support (days) [n=9 (100.0%)]
Mean (SD) (-) (-) 2.50 (0.71) (-) (-)
Median (IQR) (-,-) (-,-) 2.50 (2.25,2.75) (-,-) (-,-)